Predicting disease-related and patient-reported outcomes in older patients with breast cancer - a systematic review

The number of older patients with breast cancer has increased due to the aging general population. use a geriatric assessment in this population been advocated many studies and guidelines as it can be used identify high risk populations for early mortality toxicity. Additionally, parameters could predict relevant outcome measures. This systematic review summarizes all available evidence on predictive factors various outcomes (disease-related survival, toxicity, patient-reported outcomes), special focus outcomes, cancer.Studies were identified through literature published up September 1st 2019 PubMed database EMBASe. A total 173 included. Most investigated disease-related survival (n = 123, 71%). Toxicity was 40 (23%) mere 15% 26) outcomes. Various measures that derived from endpoints. Furthermore, among most frequently found predictors toxicity outcomes.In conclusion, study shows cancer. These findings daily clinical practice at mortality, treatment or poor functional after treatment. minority patients, showing need are tailored